Benson S J, Ruis B L, Garbers A L, Fadly A M, Conklin K F
Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.
J Virol. 1998 Dec;72(12):10301-4. doi: 10.1128/JVI.72.12.10301-10304.1998.
A new subgroup of avian leukosis virus (ALV) that includes a unique env gene, designated J, was identified recently in England. Sequence analysis of prototype English isolate HPRS-103 revealed several other unique genetic characteristics of this strain and provided information that it arose by recombination between exogenous and endogenous virus sequences. In the past several years, ALV J type viruses (ALV-J) have been isolated from broiler breeder flocks in the United States. We were interested in determining the relationship between the U.S. and English isolates of ALV-J. Based on sequence data from two independently derived U.S. field isolates, we conclude that the U.S. and English isolates of ALV-J derive from a common ancestor and are not the result of independent recombination events.
最近在英国发现了禽白血病病毒(ALV)的一个新亚群,其中包含一个独特的env基因,命名为J。对英国原型分离株HPRS - 103的序列分析揭示了该毒株的其他几个独特遗传特征,并提供信息表明它是由外源性和内源性病毒序列之间的重组产生的。在过去几年中,已从美国的肉种鸡群中分离出ALV J型病毒(ALV-J)。我们感兴趣的是确定美国和英国的ALV-J分离株之间的关系。基于两个独立来源的美国田间分离株的序列数据,我们得出结论,美国和英国的ALV-J分离株源自一个共同祖先,并非独立重组事件的结果。