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高密度相关酶:它们在血管生物学中的作用。

High density associated enzymes: their role in vascular biology.

作者信息

Navab M, Hama S Y, Hough G P, Hedrick C C, Sorenson R, La Du B N, Kobashigawa J A, Fonarow G C, Berliner J A, Laks H, Fogelman A M

机构信息

Cardiology and Cardio-thoracic Surgery, University of California, Los Angeles 90095-1679, USA.

出版信息

Curr Opin Lipidol. 1998 Oct;9(5):449-56. doi: 10.1097/00041433-199810000-00009.

DOI:10.1097/00041433-199810000-00009
PMID:9812199
Abstract

Enzymes associated with circulating HDL include lecithin: cholesterol acyl transferase, phospholipid transfer protein, cholesterol ester transfer protein, paraoxonase 1 and platelet activating factor acetylhydrolase. Together with lipoprotein lipase and hepatic lipase these enzymes produce important lipoprotein remodeling and modulate their structure and function and therefore their role in artery wall metabolism.

摘要

与循环高密度脂蛋白相关的酶包括卵磷脂胆固醇酰基转移酶、磷脂转运蛋白、胆固醇酯转运蛋白、对氧磷酶1和血小板活化因子乙酰水解酶。这些酶与脂蛋白脂肪酶和肝脂肪酶一起,可产生重要的脂蛋白重塑,并调节其结构和功能,进而影响它们在动脉壁代谢中的作用。

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