Tabakova S V, Kantardjiev T V, Mircheva V V
Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Lett Appl Microbiol. 1998 Oct;27(4):189-92. doi: 10.1046/j.1472-765x.1998.00426.x.
Tetramethyldithiooxamide (TMDTOA) is a stable and effective inhibitor of metal corrosion. The antimicrobial effects of TMDTOA and its metal compounds were investigated with regard to their use as biocides for water treatment. Growth of a variety of strains of bacteria and yeasts was completely inhibited at 400 mumol l-1 TMDTOA or its metal complexes. At 100 mg l-1 there was a 99.99% reduction in the number of viable micro-organisms; this activity persisted for 1-3 months. TMDTOA can be produced cheaply at 98% purity by a novel method, representing an alternative cost-effective water treatment agent combining corrosion-inhibiting and biocide characteristics.
四甲基二硫代乙二酰胺（TMDTOA）是一种稳定且有效的金属腐蚀抑制剂。研究了TMDTOA及其金属化合物作为水处理杀菌剂的抗菌效果。在400 μmol l-1的TMDTOA或其金属配合物存在下，多种细菌和酵母菌株的生长被完全抑制。在100 mg l-1时，活微生物数量减少了99.99%；这种活性持续1至3个月。通过一种新方法可以廉价地生产纯度为98%的TMDTOA，它是一种兼具缓蚀和杀菌特性的经济高效的水处理剂替代品。
