Xu S H, Cai Y L, Yang R M
Institute of Neurology, Anhui College of TCM, Hefei.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Jan;17(1):17-9.
To observe the effect of combination therapy of traditional and Western medicine (TCM-WM) on brainstem auditory evoked potential (BAEP) in hepatolenticular degeneration patients.
BAEP was recorded and analyzed in 65 patients with hepatolenticular degeneration (HLD) before and after decoppered TCM-WM treatment.
The peak latency (PL) and interpeak latency (IPL) of BAEP in untreated patients were greatly increased compared with those of control group, especially in the prolongations of III, V, III- V and I-V. The PL and IPL improved as improvement of clinical symptoms in HLD patients treated with TCM-WM than that in untreated patients. The abnormal rates of men and women in BAEP were decreased from 21.97% and 19.05% in untreated patients to 9.09% and 6.75% in treated patients respectively.
BAEP not only has an complementary diagnosis but also judge the efficacy of treatment on the HLD disease.
观察中西医结合疗法对肝豆状核变性患者脑干听觉诱发电位(BAEP)的影响。
对65例肝豆状核变性(HLD)患者进行驱铜中西医结合治疗,治疗前后记录并分析BAEP。
未治疗患者BAEP的峰潜伏期(PL)和峰间潜伏期(IPL)较对照组明显延长,尤其Ⅲ、Ⅴ、Ⅲ-Ⅴ及Ⅰ-Ⅴ波潜伏期延长。与未治疗患者相比,中西医结合治疗的HLD患者BAEP的PL和IPL随着临床症状的改善而改善。BAEP异常率在男性和女性患者中分别从未治疗时的21.97%和19.05%降至治疗后的9.09%和6.75%。
BAEP不仅对肝豆状核变性疾病有辅助诊断价值,而且可判断治疗效果。