Misslin R, Ropartz P, Mandel P
Pharmacol Biochem Behav. 1976 Jun;4(6):643-6. doi: 10.1016/0091-3057(76)90214-8.
The action of n-dipropylacetate (nDPA) is related to the dose. In low doses, nDPA improved the number of conditioned responses with negative reinforcement. In higher doses, the drug inhibited spontaneous and conditioned behaviour. An nDPA produces an increase in gamma-aminobutyric acid (GABA) brain level, results are discussed in relation to the inhibitory action of GABA in the central nervous system.
二丙基乙酸酯(nDPA)的作用与剂量有关。低剂量时,nDPA通过负强化改善条件反应的数量。高剂量时,该药物会抑制自发行为和条件行为。nDPA会使大脑中γ-氨基丁酸(GABA)水平升高,文中结合GABA在中枢神经系统中的抑制作用对结果进行了讨论。