Zhang J, Liu Y K, Jiang H, Ge L, Shi M J, Zhang L M
Department of Pathophysiology, Zhangjiakou Medical College.
Sheng Li Xue Bao. 1997 Aug;49(4):433-8.
The effect of intestinal lymph on blood pressure in rats was observed by the methods of lymph drainage and lymph infusion. The results obtained are as follows: (1) After 150 min of the lymph drained through the cannula of intestinal lymph duct, the blood pressure was significantly lower than that of the sham group (P < 0.05). (2) Equivalent albumin or intralipid infusion was not able to prevent the decrease in blood pressure when the lymph was lost. But in jugular-intestinal lymph duct shunt group, no significant blood pressure decrease could be seen during the drainage procedure for 4 h. (3) The blood pressure of rat with serious hemorrhagic shock could be increased significantly with a little amount of intestinal lymph infusion, and the rats survived longer than those of the control group (P < 0.05-0.01). The above results suggest that the intestinal lymph may play an important role in maintenance of blood pressure, in addition to the known function of lymphatic system by returning tissue fluid to blood and maintaining circulating blood volume.
采用淋巴引流和淋巴输注的方法观察了肠淋巴液对大鼠血压的影响。结果如下:(1)经肠淋巴管插管引流淋巴液150分钟后,血压显著低于假手术组(P<0.05)。(2)在淋巴液丢失时,输注等量白蛋白或脂肪乳不能防止血压下降。但在颈-肠淋巴管分流组,4小时引流过程中未见血压显著下降。(3)少量肠淋巴液输注可使严重失血性休克大鼠血压显著升高,且存活时间比对照组延长(P<0.05~0.01)。上述结果提示,肠淋巴液除具有淋巴系统将组织液回流入血及维持循环血容量这一已知功能外,可能在维持血压方面发挥重要作用。