Feldman R, Bacher M, Campbell N, Drover A, Chockalingam A
Department of Medicine, University of Western Ontario, London.
Can J Public Health. 1998 Sep-Oct;89(5):I16-8. doi: 10.1007/BF03404494.
Adherence to pharmacologic therapy of hypertension is low (in the range of 50-70%) and has important implications both for blood pressure control and cardiovascular complications. Based on a review of the literature using the levels of evidence grading technique, determinants of adherence to the pharmacologic therapy of hypertension have been assessed. Additionally, interventions to improve compliance were evaluated. Patient-centred, health care provider-centred and drug-specific factors have all been shown to affect adherence rates. We conclude that the extent of adherence to pharmacologic therapy is modifiable. Measurable improvements in adherence can be obtained from simplified medication regimens and a combination of behaviour strategies, including the tailoring of pill-taking to patients' daily habits and rituals, the advocacy of self-monitoring of pills and blood pressure, and the institution of reward systems.
高血压药物治疗的依从性较低(在50%-70%之间),这对血压控制和心血管并发症均具有重要影响。基于运用证据分级技术对文献的综述,已对高血压药物治疗依从性的决定因素进行了评估。此外,还对改善依从性的干预措施进行了评价。已证实,以患者为中心、以医疗服务提供者为中心以及药物特异性因素均会影响依从率。我们得出结论,药物治疗的依从程度是可以改变的。通过简化药物治疗方案以及结合行为策略,包括根据患者的日常习惯和规律调整服药方式、提倡自我监测服药情况和血压,以及建立奖励机制,可以实现依从性的显著提高。