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孕期红细胞压积率及溶血卵磷脂水平的变化

Erythrocyte packing rates and altered lysolecithin levels during pregnancy.

作者信息

Gillett M P

出版信息

Rev Bras Pesqui Med Biol. 1976 Sep;9(4):199-205.

PMID:981739
Abstract

The rate of packing of erythrocytes during centrifugation has been measured as an index of erythrocyte flexibility. Exposure of erythrocytes to sub-haemolytic concentrations of lysolecithin decreased their packing rate indicating that the cells had become less flexible. Erythrocyte packing rates and plasma lysolecithin levels have been measured in a series of forty pregnant and non-pregnant women. The plasma concentrations of lysolecithin were significantly lower in pregnant women when compared with non-pregnant women. In contrast to this, the plasma concentrations of total phospholipid and lecithin were elevated during pregnancy. Erythrocyte packing rates were increased during pregnancy and a statistically very significant negative correlation was found between erythrocyte packing rate and plasma lysolecithin concentration.

摘要

红细胞在离心过程中的堆积率已被测定,作为红细胞柔韧性的指标。将红细胞暴露于亚溶血浓度的溶血卵磷脂中会降低其堆积率,这表明细胞的柔韧性降低。在一系列40名孕妇和非孕妇中测量了红细胞堆积率和血浆溶血卵磷脂水平。与非孕妇相比,孕妇血浆中溶血卵磷脂的浓度显著更低。与此相反,孕期总磷脂和卵磷脂的血浆浓度升高。孕期红细胞堆积率增加,并且在红细胞堆积率与血浆溶血卵磷脂浓度之间发现了具有统计学意义的显著负相关。

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