Gregory S H, Wing E J
Dept of Medicine, University of Pittsburgh School of Medicine, PA 15213-2582, USA.
Immunol Today. 1998 Nov;19(11):507-10. doi: 10.1016/s0167-5699(98)01319-x.
Most relevant textbooks characterize phagocytosis by Kupffer cells as the principal mechanism for clearing bacterial pathogens from the bloodstream and eliminating them from the liver. Here, Stephen Gregory and Edward Wing discuss recent evidence indicating that the actual mechanism is far more complicated, dependent upon the complex interaction of Kupffer cells with neutrophils that immigrate into the liver following infection.
大多数相关教科书将库普弗细胞的吞噬作用描述为从血液中清除细菌病原体并将其从肝脏中清除的主要机制。在此，斯蒂芬·格雷戈里和爱德华·温讨论了最近的证据，这些证据表明实际机制要复杂得多，它依赖于库普弗细胞与感染后迁移到肝脏的中性粒细胞的复杂相互作用。
