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肿胀性多发性硬化病变的生理磁共振成像

Physiologic MRI of a tumefactive multiple sclerosis lesion.

作者信息

Ernst T, Chang L, Walot I, Huff K

机构信息

Department of Radiology, Harbor-UCLA Medical Center, Torrance, CA 90502, USA.

出版信息

Neurology. 1998 Nov;51(5):1486-8. doi: 10.1212/wnl.51.5.1486.

DOI:10.1212/wnl.51.5.1486
PMID:9818892
Abstract

Structural and physiologic MRI were performed after subacute onset of left hemiparesis in a patient with MS. MRI showed a large ring-enhancing lesion with surrounding edema and mass effect; differential diagnosis included a neoplasm or a large MS plaque. Physiologic MRI showed reduced blood flow and magnetization transfer, as well as increased diffusion, in the large lesion. Because these findings suggested a tumefactive MS plaque rather than a neoplasm, the patient received steroid treatment for acute MS exacerbation. Three months later the patient improved clinically and on MRI.

摘要

在一名多发性硬化症(MS)患者出现左半身轻瘫亚急性发作后,进行了结构和生理磁共振成像(MRI)检查。MRI显示一个大的环形强化病灶,伴有周围水肿和占位效应;鉴别诊断包括肿瘤或大的MS斑块。生理MRI显示该大病灶处血流减少、磁化传递降低以及扩散增加。由于这些发现提示为肿胀性MS斑块而非肿瘤,该患者接受了针对急性MS加重的类固醇治疗。三个月后,患者在临床和MRI检查方面均有改善。

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