苏云金芽孢杆菌酶消化的δ内毒素：对培养昆虫细胞的影响
Bacillus thuringiensis enzyme-digested delta endotoxin: effect on cultured insect cells.
作者信息
Murphy D W, Sohi S S, Fast P G
出版信息
Science. 1976 Nov 26;194(4268):954-6. doi: 10.1126/science.982053.
PMID:982053
Abstract
Cells from three insect cell lines responded to the enzyme-digested delta endotoxin of Bacillus thuringiensis with swelling, lysis, and vesicle formation. Sufficient toxin was taken up in 1 minute to cause half-maximal cell damage. Cytoxic activity was neutralized by specific antiserum to the endotoxin.
摘要
来自三种昆虫细胞系的细胞对苏云金芽孢杆菌经酶消化的δ-内毒素产生反应，出现肿胀、裂解和囊泡形成。1分钟内摄取的毒素量足以造成半数最大细胞损伤。细胞毒性活性可被针对该内毒素的特异性抗血清中和。
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