Manny J, Romanoff H, Hyam E, Manny N
Surgery. 1976 Nov;80(5):641-3.
In 15 patients undergoing aortofemoral bypass, partial thromboplastin time (PTT) tests before and following intravenous administration of 75 U. per kilogram of heparin at zero, 30, 60, 90, and 120 minutes were determined for study of control of anticoagulant adequacy. The results demonstrate clearly that this amount provides excellent protection against thrombosis without bleeding complications. For intraoperative assay of heparin level effectiveness, the PTT test is advised. This test showed that a value of 250 percent of control still existed 75 minutes following the administration of heparin.
在15例行主动脉股动脉旁路移植术的患者中，于静脉注射每千克体重75单位肝素后的0、30、60、90和120分钟测定部分凝血活酶时间（PTT），以研究抗凝充分性的控制情况。结果清楚地表明，该剂量可提供极佳的抗血栓形成保护作用，且无出血并发症。对于术中肝素水平有效性的测定，建议采用PTT试验。该试验显示，肝素给药75分钟后，PTT值仍为对照值的250%。
