Bogden P E, Abbott R D, Williamson P, Onopa J K, Koontz L M
Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.
J Gen Intern Med. 1998 Nov;13(11):740-5. doi: 10.1046/j.1525-1497.1998.00225.x.
To assess the effect of a physician and pharmacist teamwork approach to uncontrolled hypertension in a medical resident teaching clinic, for patients who failed to meet the recommended goals of the fifth Joint National Commission on Detection, Evaluation and Treatment of High Blood Pressure.
Physician and pharmacist teamwork can improve the rate of meeting national blood pressure goals in patients with previously uncontrolled hypertension.
A single-blinded randomized controlled trial lasting 6 months.
A primary care outpatient teaching clinic.
A sample of 95 adult hypertensive patients who failed to meet national blood pressure goals based on three consecutive visits over a 6-month period.
Patients were randomly assigned to a control arm of standard medical care or to an intervention arm in which a physician and pharmacist worked together as a team.
At study completion, the percentage of patients achieving national goals due to intervention was more than double the percentage in the control arm (55% vs 20%, p < .001). Systolic blood pressure declined 23 mm Hg in the intervention arm versus 11 mm Hg in the control arm (p < .01). Diastolic blood pressure declined 14 and 3 mm Hg in the intervention and control arms, respectively (p < .001). The intervention worked equally as well in men and women and demonstrated noticeable promise in a minority of mixed-ancestry Hawaiians in whom hypertension is of special concern.
Patients who fail to achieve national blood pressure goals under standard outpatient medical care may benefit from a program that includes a physician and pharmacist teamwork approach.
对于未能达到美国国家高血压检测、评估与治疗联合委员会(JNC)第五次报告推荐目标的患者,评估在住院医师教学门诊中医生与药剂师团队协作治疗方案对控制高血压的效果。
医生与药剂师团队协作能够提高既往高血压控制不佳患者达到国家血压控制目标的比例。
一项为期6个月的单盲随机对照试验。
一家初级保健门诊教学诊所。
选取95例成年高血压患者,这些患者在6个月内连续3次就诊血压均未达到国家血压控制目标。
患者被随机分为接受标准医疗护理的对照组和医生与药剂师团队协作的干预组。
研究结束时,干预组达到国家目标的患者比例比对照组高出一倍多(55%对20%,p<0.001)。干预组收缩压下降23mmHg,对照组下降11mmHg(p<0.01)。干预组和对照组舒张压分别下降14mmHg和3mmHg(p<0.001)。该干预措施在男性和女性患者中效果相同,并且在少数高血压问题尤为突出的夏威夷混血人群中也显示出显著效果。
在标准门诊医疗护理下未能达到国家血压控制目标的患者,可能会从包含医生与药剂师团队协作的治疗方案中获益。