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本文引用的文献

1
The physician and pharmacist team. An effective approach to cholesterol reduction.医生和药剂师团队。降低胆固醇的有效方法。
J Gen Intern Med. 1997 Mar;12(3):158-64. doi: 10.1007/s11606-006-5023-7.
2
The fifth report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC V).全国高血压检测、评估与治疗联合委员会第五次报告(JNC V)
Arch Intern Med. 1993 Jan 25;153(2):154-83.
3
Trends in the prevalence, awareness, treatment, and control of hypertension in the adult US population. Data from the health examination surveys, 1960 to 1991.美国成年人群中高血压患病率、知晓率、治疗率和控制率的趋势。来自1960年至1991年健康检查调查的数据。
Hypertension. 1995 Jul;26(1):60-9. doi: 10.1161/01.hyp.26.1.60.
4
High mortality rates in Native Hawaiians.夏威夷原住民的高死亡率。
Hawaii Med J. 1995 Sep;54(9):723-9.
5
Improving drug-therapy decisions through educational outreach. A randomized controlled trial of academically based "detailing".通过教育推广改善药物治疗决策。一项基于学术的“详细介绍”随机对照试验。
N Engl J Med. 1983 Jun 16;308(24):1457-63. doi: 10.1056/NEJM198306163082406.
6
The effect of clinical pharmacy services on patients with essential hypertension.临床药学服务对原发性高血压患者的影响。
Circulation. 1973 Nov;48(5):1104-11. doi: 10.1161/01.cir.48.5.1104.
7
Questioning the proof for effectiveness of pharmacist intervention in blood pressure control.
Am J Hosp Pharm. 1987 Jan;44(1):68-70.
8
Effect of pharmacist intervention on control of resistant hypertension.
Am J Hosp Pharm. 1986 Apr;43(4):905-9.
9
Effects of the National Institutes of Health Consensus Development Program on physician practice.美国国立卫生研究院共识发展项目对医生临床实践的影响。
JAMA. 1987 Nov 20;258(19):2708-13.
10
Do practice guidelines guide practice? The effect of a consensus statement on the practice of physicians.实践指南能指导实践吗?一项共识声明对医生实践的影响。
N Engl J Med. 1989 Nov 9;321(19):1306-11. doi: 10.1056/NEJM198911093211906.

比较标准护理与由医生和药剂师组成的团队治疗方法对控制不佳的高血压的效果。

Comparing standard care with a physician and pharmacist team approach for uncontrolled hypertension.

作者信息

Bogden P E, Abbott R D, Williamson P, Onopa J K, Koontz L M

机构信息

Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.

出版信息

J Gen Intern Med. 1998 Nov;13(11):740-5. doi: 10.1046/j.1525-1497.1998.00225.x.

DOI:10.1046/j.1525-1497.1998.00225.x
PMID:9824519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1497023/
Abstract

OBJECTIVE

To assess the effect of a physician and pharmacist teamwork approach to uncontrolled hypertension in a medical resident teaching clinic, for patients who failed to meet the recommended goals of the fifth Joint National Commission on Detection, Evaluation and Treatment of High Blood Pressure.

HYPOTHESIS

Physician and pharmacist teamwork can improve the rate of meeting national blood pressure goals in patients with previously uncontrolled hypertension.

DESIGN

A single-blinded randomized controlled trial lasting 6 months.

SETTING

A primary care outpatient teaching clinic.

PATIENTS

A sample of 95 adult hypertensive patients who failed to meet national blood pressure goals based on three consecutive visits over a 6-month period.

INTERVENTION

Patients were randomly assigned to a control arm of standard medical care or to an intervention arm in which a physician and pharmacist worked together as a team.

MAIN RESULTS

At study completion, the percentage of patients achieving national goals due to intervention was more than double the percentage in the control arm (55% vs 20%, p < .001). Systolic blood pressure declined 23 mm Hg in the intervention arm versus 11 mm Hg in the control arm (p < .01). Diastolic blood pressure declined 14 and 3 mm Hg in the intervention and control arms, respectively (p < .001). The intervention worked equally as well in men and women and demonstrated noticeable promise in a minority of mixed-ancestry Hawaiians in whom hypertension is of special concern.

CONCLUSIONS

Patients who fail to achieve national blood pressure goals under standard outpatient medical care may benefit from a program that includes a physician and pharmacist teamwork approach.

摘要

目的

对于未能达到美国国家高血压检测、评估与治疗联合委员会(JNC)第五次报告推荐目标的患者,评估在住院医师教学门诊中医生与药剂师团队协作治疗方案对控制高血压的效果。

假设

医生与药剂师团队协作能够提高既往高血压控制不佳患者达到国家血压控制目标的比例。

设计

一项为期6个月的单盲随机对照试验。

地点

一家初级保健门诊教学诊所。

患者

选取95例成年高血压患者,这些患者在6个月内连续3次就诊血压均未达到国家血压控制目标。

干预措施

患者被随机分为接受标准医疗护理的对照组和医生与药剂师团队协作的干预组。

主要结果

研究结束时,干预组达到国家目标的患者比例比对照组高出一倍多(55%对20%,p<0.001)。干预组收缩压下降23mmHg,对照组下降11mmHg(p<0.01)。干预组和对照组舒张压分别下降14mmHg和3mmHg(p<0.001)。该干预措施在男性和女性患者中效果相同,并且在少数高血压问题尤为突出的夏威夷混血人群中也显示出显著效果。

结论

在标准门诊医疗护理下未能达到国家血压控制目标的患者,可能会从包含医生与药剂师团队协作的治疗方案中获益。