McBean A M, Foster S O, Herrmann K L, Gateff C
Trans R Soc Trop Med Hyg. 1976;70(3):206-12. doi: 10.1016/0035-9203(76)90040-7.
A mass measles immunization campaign carried out in Yaoundé, Cameroun, has been evaluated. Sixty per cent of the children were immune to measles at the time of the campaign. Only 51% of the susceptible children received vaccine. This was caused by a lack of attendance at the vaccination centres and errors in the selection of children given vaccine. The vaccine administered was relatively ineffective: 40% seroconversion. Difficulties which probably contributed to the low seroconversion rate included sub-optimal vaccine titre, inadequate doses of vaccine, and the relatively long time of vaccine utilization under tropical temperatures. Overall, 83% of the vaccine given to the vaccinating team was wasted. Future immunization campaigns can be improved through better screening of the children, improved handling of the vaccine, the use of marker vaccines, and improved health education.
在喀麦隆雅温得开展的大规模麻疹免疫接种活动已得到评估。在开展活动时,60%的儿童对麻疹具有免疫力。只有51%的易感儿童接种了疫苗。这是由于疫苗接种中心的出勤率低以及在选择接种疫苗儿童时出现错误所致。所接种的疫苗相对无效:血清转化率为40%。可能导致血清转化率低的因素包括疫苗效价欠佳、疫苗剂量不足以及在热带温度下疫苗使用时间相对较长。总体而言,发放给接种团队的疫苗有83%被浪费。未来的免疫接种活动可通过更好地筛查儿童、改进疫苗处理方式、使用标记疫苗以及加强健康教育来加以改善。