Threlfall E J, Ward L R, Hampton M D, Ridley A M, Rowe B, Roberts D, Gilbert R J, Van Someren P, Wall P G, Grimont P
Laboratory of Enteric Pathogens, Central Public Health Laboratory, London, UK.
Epidemiol Infect. 1998 Oct;121(2):289-93. doi: 10.1017/s0950268898001149.
Molecular analyses based on plasmid profile typing and pulsed-field gel electrophoresis have defined a strain of Salmonella enterica serotype Anatum associated with the consumption of a particular brand of formula-dried milk responsible for an outbreak in late 1996/early 1997 involving 15 infants and 2 relatives in the UK, and 2 infants in France. The study has demonstrated the value of laboratory-based surveillance involving identification of the outbreak strain at the molecular level coupled with food microbiology and targeted epidemiological investigations, and has highlighted the importance of rapid communication and subsequent international collaboration through the European Union-funded Salm-Net salmonella surveillance network.
基于质粒图谱分型和脉冲场凝胶电泳的分子分析确定了一株肠炎沙门氏菌血清型阿纳托姆,它与食用某一特定品牌的配方奶粉有关,该奶粉导致了1996年末/1997年初在英国爆发的一起疫情,涉及15名婴儿和2名亲属,以及法国的2名婴儿。该研究证明了基于实验室的监测的价值,包括在分子水平上鉴定疫情菌株,结合食品微生物学和有针对性的流行病学调查,并强调了通过欧盟资助的Salm-Net沙门氏菌监测网络进行快速沟通和随后的国际合作的重要性。