Wang M, Hench L L, Bonfield W
Interdisciplinary Research Centre in Biomedical Materials, Queen Mary and Westfield College, University of London, United Kingdom.
J Biomed Mater Res. 1998 Dec 15;42(4):577-86. doi: 10.1002/(sici)1097-4636(19981215)42:4<577::aid-jbm14>3.0.co;2-2.
Particulate 45S5 Bioglass with an average size of 46 microm was incorporated into a high density polyethylene (HDPE) for potential medical applications. Composites with Bioglass volumes of 10, 20, and 40% were produced by a manufacturing process consisting of blending, compounding, powdering, and compression molding. The Bioglass particles were well dispersed, and their homogeneous distribution in the polymer matrix, achieved after compounding, was retained during subsequent composite processing. The Young's modulus and microhardness of the composites increased with an increase in Bioglass volume while the tensile strength and fracture strain decreased. Fourier transform infrared spectra, obtained from Bioglass/HDPE samples exposed for 20 h at 37 degrees C to a simulated body fluid (SBF-9), demonstrated that composites of all the compositions examined developed the surface biological apatite layer equivalent to that for bulk Bioglass.
平均尺寸为46微米的颗粒状45S5生物玻璃被掺入高密度聚乙烯（HDPE）中，用于潜在的医学应用。通过包括混合、复合、粉末化和压缩成型的制造工艺制备了生物玻璃体积分数为10%、20%和40%的复合材料。生物玻璃颗粒分散良好，在复合后实现的其在聚合物基体中的均匀分布在随后的复合材料加工过程中得以保留。复合材料的杨氏模量和显微硬度随生物玻璃体积分数的增加而增加，而拉伸强度和断裂应变则降低。对在37℃下暴露于模拟体液（SBF-9）20小时的生物玻璃/HDPE样品进行傅里叶变换红外光谱分析，结果表明，所有测试组成的复合材料都形成了与块状生物玻璃相当的表面生物磷灰石层。
