Løken T, Aleksandersen M, Reid H, Pow I
Norwegian College of Veterinary Medicine, Oslo, Norway.
Vet Rec. 1998 Oct 24;143(17):464-7. doi: 10.1136/vr.143.17.464.
This paper describes the first cases of malignant catarrhal fever (MCF) in pigs in which the diagnosis was verified aetiologically by polymerase chain reaction (PCR) and DNA analysis and by the demonstration of antibodies. Three pigs on two separate premises showed clinical signs, gross pathological and histopathological lesions which were in many respects similar to those of MCF in ruminants. The pigs were housed adjacent to sheep and DNA of ovine herpesvirus-2 (OHV-2) was detected by PCR in tissues of all the pigs. In addition, antibody to alcelaphine herpesvirus-1 was detected in the serum of the pigs and in five in-contact sheep. It is concluded that the disease described is MCF of pigs caused by OHV-2.
本文描述了首例猪恶性卡他热（MCF）病例，通过聚合酶链反应（PCR）、DNA分析及抗体检测从病因学上确诊。两个不同猪场的三头猪出现了临床症状、大体病理和组织病理学病变，这些病变在许多方面与反刍动物的MCF相似。这些猪与绵羊相邻饲养，通过PCR在所有猪的组织中检测到了绵羊疱疹病毒2型（OHV-2）的DNA。此外，在猪血清及五只接触过的绵羊中检测到了对鹿疱疹病毒1型的抗体。结论是所描述的疾病是由OHV-2引起的猪MCF。
