Niĭt M I
Vopr Pitan. 1976 Sep-Oct(5):52-4.
Renal excretion of xanthurenic acid without any tryptophan load, passage of 4-pyridoxic acid with diurnal urine and its excretion with urine collected during 1 hour in the morning on an empty stomach were investigated in 86 practically healthy infants and in 77 others with acute respiratory viral infections aged from two weeks to one year. Investigations of the tryptophan tolerance in infants yielded negative results, viz. on administering to them of D,L-tryptophan in a load dose the infants started vomiting. Practically healthy infants did not excrete xanthurenic acid, while the renal excretion of 4-pyridoxic acid remained within normal limits. In patients at the height of the disease the passage of 4-pyridoxic acid steeply increased. In 9 of them xanthurenic acid appeared in the diurnal urine. In the quiscent stage of the affection in two infants xanthurenuria continued against the general background of diminished excretion of 4-pyridoxic acid. There is no reason to relate the disclosed xanthurenuria in sick infants with the state of hypovitaminosis in them.
对86名实际健康的婴儿以及77名年龄从两周至一岁的急性呼吸道病毒感染患儿，研究了无任何色氨酸负荷情况下尿黄尿酸的肾排泄、4 - 吡哆酸随昼夜尿液的排出情况以及空腹清晨1小时内尿液中4 - 吡哆酸的排泄情况。对婴儿色氨酸耐受性的研究结果为阴性，即给婴儿给予负荷剂量的D,L - 色氨酸时，婴儿开始呕吐。实际健康的婴儿不排泄尿黄尿酸，而4 - 吡哆酸的肾排泄仍在正常范围内。在疾病高峰期的患者中，4 - 吡哆酸的排出量急剧增加。其中9名患者的昼夜尿液中出现了尿黄尿酸。在两名婴儿病情静止期，尿黄尿酸尿在4 - 吡哆酸排泄减少的总体背景下仍持续存在。没有理由将患病婴儿中发现的尿黄尿酸尿与他们体内维生素缺乏状态联系起来。
