Mowé M, Bøhmer T, Haug E
Medisinsk avdeling, Aker sykehus, Oslo.
Tidsskr Nor Laegeforen. 1998 Oct 20;118(25):3929-31.
Vitamin D status, measured as serum calcidiol concentration, was studied in a group of 273 recently hospitalised patients at Aker University Hospital and compared to a group of 98 persons living in their own homes, all living in Oslo and all above 70 years of age. We found lower serum calcidiol concentrations in the hospital group than among people living in their own homes, in men as well as in women (mean +/- SD, 40.4 nmol/l +/- 23.2 vs 59.6 nmol/l +/- 28.9 in men and 37.5 nmol/l +/- 22.6 vs 48.5 +/- 20.3 in women). 34% of the men and 49% of the women in the hospital group had vitamin D deficiency (se. calcidiol < 20 nmol/l). There was no seasonal variation in the hospitalised group; the group living at home did show seasonal variations, with highest levels in late autumn (62.2 nmol/l) and lowest levels in February (42.7 nmol/l). The low levels of calcidiol concentration may contribute to the high prevalence of hip-fracture among elderly in Oslo.
以血清骨化二醇浓度衡量的维生素D状况,在阿克尔大学医院的273名近期住院患者中进行了研究,并与98名居家生活的人进行了比较,所有研究对象均居住在奥斯陆,年龄均在70岁以上。我们发现,住院组的血清骨化二醇浓度低于居家生活的人,男性和女性均如此(均值±标准差,男性为40.4 nmol/l±23.2,居家生活男性为59.6 nmol/l±28.9;女性为37.5 nmol/l±22.6,居家生活女性为48.5±20.3)。住院组中34%的男性和49%的女性存在维生素D缺乏(血清骨化二醇<20 nmol/l)。住院组没有季节性变化;居家生活组确实表现出季节性变化,深秋时水平最高(62.2 nmol/l),2月时水平最低(42.7 nmol/l)。骨化二醇浓度偏低可能是奥斯陆老年人髋部骨折高发的原因之一。