Levy W C, Cerqueira M D, Harp G D, Johannessen K A, Abrass I B, Schwartz R S, Stratton J R
Department of Medicine, Seattle Veterans Affairs Medical Center and the University of Washington, USA.
Am J Cardiol. 1998 Nov 15;82(10):1236-41. doi: 10.1016/s0002-9149(98)00611-0.
Heart rate variability (HRV) (SD of the RR interval), an index of parasympathetic tone, was measured at rest and during exercise in 13 healthy older men (age 60 to 82 years) and 11 healthy young men (age 24 to 32 years) before and after 6 months of aerobic exercise training. Before exercise training, the older subjects had a 47% lower HRV at rest compared with the young subjects (31 +/- 5 ms vs 58 +/- 4 ms, p = 0.0002). During peak exercise, the older subjects had less parasympathetic withdrawal than the young subjects (-45% vs -84%, p = 0.0001). Six months of intensive aerobic exercise training increased maximum oxygen consumption by 21% in the older group and 17% in the young group (analysis of variance: overall training effect, p = 0.0001; training effect in young vs old, p = NS). Training decreased the heart rate at rest in both the older (-9 beats/min) and the young groups (-5 beats/min, before vs after, p = 0.0001). Exercise training increased HRV at rest (p = 0.009) by 68% in the older subjects (31 +/- 5 ms to 52 +/- 8 ms) and by 17% in the young subjects (58 +/- 4 ms to 68 +/- 6 ms). Exercise training increases parasympathetic tone at rest in both the healthy older and young men, which may contribute to the reduction in mortality associated with regular exercise.
心率变异性（HRV）（RR间期标准差）是副交感神经张力的一个指标，在13名健康老年男性（年龄60至82岁）和11名健康年轻男性（年龄24至32岁）进行6个月有氧运动训练前后，于静息状态和运动期间进行了测量。在运动训练前，老年受试者静息时的HRV比年轻受试者低47%（31±5毫秒对58±4毫秒，p = 0.0002）。在运动峰值时，老年受试者的副交感神经撤离比年轻受试者少（-45%对-84%，p = 0.0001）。6个月的强化有氧运动训练使老年组的最大耗氧量增加了21%，年轻组增加了17%（方差分析：总体训练效果，p = 0.0001；年轻组与老年组的训练效果，p = 无显著性差异）。训练使老年组（-9次/分钟）和年轻组（-5次/分钟，训练前与训练后，p = 0.0001）的静息心率均降低。运动训练使老年受试者静息时的HRV增加了68%（从31±5毫秒增加到52±8毫秒，p = 0.009），年轻受试者增加了17%（从58±4毫秒增加到68±6毫秒）。运动训练增加了健康老年男性和年轻男性静息时的副交感神经张力，这可能有助于降低与定期运动相关的死亡率。
