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[溃疡性结肠炎全结肠直肠切除术后的生活质量]

[Quality of life after proctocolectomy for ulcerative colitis].

作者信息

Heuschen U A, Heuschen G, Herfarth C

机构信息

Chirurgische Klinik und Poliklinik, Universität Heidelberg.

出版信息

Chirurg. 1998 Oct;69(10):1045-51.

PMID:9833183
Abstract

Nowadays, restorative proctocolectomy is considered the "gold standard" in the surgical therapy of ulcerative colitis. Alternative procedures such as Brooke ileostomy or Kock pouch are limited to special indications. Preservation of function is the decisive advantage of the ileoanal pouch, but preservation of function is not equal to quality of life. Quality of life is a multidimensional concept that is difficult to define and measure. Quality of life can only be assessed by standardized and validated quality-of-life questionnaires. Preoperatively, patients with ulcerative colitis have a restricted quality of life, depending on the intensity of their disease. Proctocolectomy is the curative therapy and improves quality of life. When evaluating quality of life it is not essential if patients are treated by Brooke ileostomy or restorative proctocolectomy. The advantage of restorative proctocolectomy is the improvement in some aspects such as sexuality and physical activity. The "Total Quality-of-Life Index" is not improved. Preoperatively, patients should be informed that preservation of function by restorative proctocolectomy is accompanied by an increased postoperative morbidity in comparison to other procedures. Decreased quality-of-life results when complications occur postoperatively that cannot be controlled over a long period of time. In some cases excision of the ileoanal pouch may be the most sensible way of solving the problems. On the other hand, patients without complications and good function after ileoanal pouch procedure may achieve a quality of life comparable to that of healthy controls. Preoperatively, patients should be aware of this risk-benefit relationship and should share the responsibility of the decision for or against restorative proctocolectomy.

摘要

如今,全结直肠切除回肠贮袋肛管吻合术被认为是溃疡性结肠炎外科治疗的“金标准”。诸如布鲁克回肠造口术或科克贮袋术等替代手术仅限于特殊适应症。保留功能是回肠肛管贮袋的决定性优势,但保留功能并不等同于生活质量。生活质量是一个多维概念,难以定义和衡量。生活质量只能通过标准化和经过验证的生活质量问卷来评估。术前,溃疡性结肠炎患者的生活质量受限,这取决于其疾病的严重程度。全结直肠切除术是一种根治性治疗方法,可提高生活质量。在评估生活质量时,患者接受布鲁克回肠造口术还是全结直肠切除回肠贮袋肛管吻合术治疗并不重要。全结直肠切除回肠贮袋肛管吻合术的优势在于在某些方面有所改善,如性功能和身体活动。“总体生活质量指数”并未提高。术前应告知患者,与其他手术相比,全结直肠切除回肠贮袋肛管吻合术保留功能的同时术后发病率会增加。如果术后出现长期无法控制的并发症,生活质量会下降。在某些情况下,切除回肠肛管贮袋可能是解决问题的最明智方法。另一方面,回肠肛管贮袋手术后无并发症且功能良好的患者可能获得与健康对照相当的生活质量。术前,患者应了解这种风险效益关系,并应共同承担决定是否进行全结直肠切除回肠贮袋肛管吻合术的责任。

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