Frei P C, Grob P J
Division d'immunologie et d'allergie, CHUV, Lausanne.
Soz Praventivmed. 1998;43 Suppl 1:S10-3, S84-7. doi: 10.1007/BF02042165.
This paper is a short summary on the usefulness of two antigens (HBsAg and HBeAg), three antibodies (anti-HBc, anti-HBe and anti-HBs) and of HBV DNA, as markers for the diagnosis and the follow-up of hepatitis B. The significance of each of these markers at the various stages of disease history, a few patterns of co-existence of some of these markers and the occurrence of mutations in the core and pre-core regions of the genome are also described. The various indications for measuring HBV DNA, in addition to the classical serological markers, are also mentioned.
