McCarter M D, Gomez M E, Daly J M
Department of Surgery, New York Hospital-Cornell University Medical Center, New York, NY, USA.
J Gastrointest Surg. 1997 May-Jun;1(3):278-85; discussion 285. doi: 10.1016/s1091-255x(97)80121-7.
For a variety of reasons, enteral feeding is frequently delayed following major abdominal surgery. The purpose of this study was to evaluate prospectively the feasibility and tolerance of early jejunal feeding following major upper gastrointestinal surgery. Beginning on postoperative day 1, patients (n = 167) received a full-strength enteral formula at the rate of 25 ml/hr through a jejunal feeding tube. Diets were advanced to the calculated target rate (25 kcal/kg/day) by postoperative day 4. Complications of tube feeding, calories received, and patient symptoms were recorded daily. There were no major complications or deaths resulting from placement of a jejunal tube or from early enteral feeding. Patients had abdominal symptoms such as cramping, distention, nausea, and diarrhea on 9%, 18%, 4%, and 24% of all feeding days, respectively. The majority of these symptoms, with the exception of diarrhea, were graded as mild. Patients undergoing surgery for pancreatic malignancy had significantly more diarrhea than patients undergoing esophagectomy or gastrectomy. Despite these differences in symptoms, patients received an average of 78% of their targeted caloric goal by postoperative day 4 and maintained this level throughout the study. Early enteral feeding for patients undergoing esophageal, gastric, or pancreatic resections is both safe and feasible despite the occurrence of predominantly mild gastrointestinal symptoms.
由于多种原因,腹部大手术后肠内喂养常常延迟。本研究的目的是前瞻性评估上腹部大手术后早期空肠喂养的可行性和耐受性。从术后第1天开始,患者(n = 167)通过空肠喂养管以25毫升/小时的速度接受全强度肠内配方奶。到术后第4天,饮食逐渐增加至计算出的目标速率(25千卡/千克/天)。每天记录管饲并发症、摄入的热量和患者症状。空肠管置入或早期肠内喂养均未导致重大并发症或死亡。患者在所有喂养日中分别有9%、18%、4%和24%出现腹部症状,如绞痛、腹胀、恶心和腹泻。除腹泻外,这些症状大多为轻度。接受胰腺恶性肿瘤手术的患者腹泻明显多于接受食管切除术或胃切除术的患者。尽管症状存在这些差异,但患者在术后第4天平均摄入了目标热量的78%,并在整个研究过程中维持了这一水平。对于接受食管、胃或胰腺切除术的患者,早期肠内喂养尽管主要出现轻度胃肠道症状,但既安全又可行。