Bode C, Bode J C, Erhardt J G, French B A, French S W
Institut für Biologische Chemie and Ernährungswissenschaft, F.B., Ernährungs Physiologie, Universität Hohenheim, Stuttgart, Germany.
Alcohol Clin Exp Res. 1998 Nov;22(8):1803-5.
We analyzed meat products and alcoholic beverage preference in patients with the three stages of alcoholic liver disease (ALD) compared with controls using diet history data. Daily consumption of total alcohol, types of alcoholic beverages, and types of meat and meat products in grams was obtained by dietary history taken from patients with biopsy proven stage of ALD. A strong association was found between the ALD subjects and total alcohol and beer consumption. There was a significant increase in the consumption of total pig products, pork, and offal in the ALD groups compared with controls. There was a significant positive correlation between beer consumption and pork in alcoholic hepatitis, total pork products in alcoholic hepatitis, and cirrhosis and offal in alcoholic hepatitis and cirrhosis. There was no correlation with the fatty liver stage of ALD. The strongest correlation was between beer and total pig products in the alcoholic hepatitis group. Wine consumption was negatively correlated with the consumption of pig products and beer in the alcoholic cirrhosis group. In conclusion, the association of total pig product consumption with cirrhosis mortality in various countries was validated by personal diet history data obtained from ALD patients in a tested clinical microcosm. The results suggest that this association may be modified by the type of alcoholic beverage that is preferentially consumed.
我们使用饮食史数据，分析了酒精性肝病（ALD）三个阶段的患者与对照组相比对肉类产品和酒精饮料的偏好。通过对经活检证实为ALD阶段的患者进行饮食史调查，获取每日酒精总摄入量、酒精饮料类型以及肉类和肉类产品的克数。在ALD受试者与酒精总摄入量和啤酒消费量之间发现了密切关联。与对照组相比，ALD组的猪产品、猪肉和内脏的消费量显著增加。在酒精性肝炎中，啤酒消费量与猪肉、酒精性肝炎中猪产品总量、肝硬化以及酒精性肝炎和肝硬化中的内脏之间存在显著正相关。与ALD的脂肪肝阶段无相关性。酒精性肝炎组中啤酒与猪产品总量之间的相关性最强。在酒精性肝硬化组中，葡萄酒消费量与猪产品和啤酒的消费量呈负相关。总之，在一个经过测试的临床缩影中，从ALD患者获得的个人饮食史数据证实了不同国家猪产品总消费量与肝硬化死亡率之间的关联。结果表明，这种关联可能会因优先消费的酒精饮料类型而改变。
