Rugg M D, Walla P, Schloerscheidt A M, Fletcher P C, Frith C D, Dolan R J
Wellcome Brain Research Group, School of Psychology, University of St Andrews, UK.
Exp Brain Res. 1998 Nov;123(1-2):18-23. doi: 10.1007/s002210050540.
The probability that words would be recollected during tests of recognition memory was varied by manipulating depth of processing at study. Experiment 1 employed scalp-recorded event-related potentials (ERPs), and identified as a correlate of recollection a late (onset c. 500 ms), strongly left-lateralized positive-going modulation of the ERP waveform. The findings from experiment 2, which employed positron emission tomography (PET), indicated that recollection was associated with activation of the left hippocampal formation together with an extensive region of left temporal and frontal cortex. The findings support current ideas about the role of the hippocampal formation in episodic memory retrieval, and provide complementary information about the time course and localization of the cortical correlates of the recollection of recently experienced words.
在识别记忆测试中，通过在学习时操纵加工深度来改变单词被回忆起的概率。实验1采用头皮记录的事件相关电位（ERP），并将ERP波形中一个晚期（约500毫秒开始）、强烈左偏侧化的正向调制识别为回忆的一个相关指标。实验2采用正电子发射断层扫描（PET），其结果表明，回忆与左侧海马结构以及左侧颞叶和额叶皮质的广泛区域的激活有关。这些发现支持了当前关于海马结构在情景记忆检索中作用的观点，并提供了关于近期经历单词回忆的皮质相关指标的时间进程和定位的补充信息。
