Lukkarinen H
Department of Nursing, University of Oulu, Oulu University Hospital, Finland.
Nurs Res. 1998 Nov-Dec;47(6):337-43. doi: 10.1097/00006199-199811000-00007.
Coronary artery disease (CAD) constitutes a considerable financial burden on society in Finland; it is the cause of death of approximately 7,500 men and 6,500 women annually in a population of 5 million.
The purpose of this study was to assess the changes in the quality of life (QOL) of patients with CAD treated by medication, percutaneous transluminal coronary angioplasty (PTCA), and coronary artery bypass surgery (CABS) during 1 year.
The study population consisted of 280 patients with CAD. One hundred patients had been referred to CABS and another 100 to PTCA, whereas 80 patients were on drug therapy. The patients assessed their health status and QOL in terms of functional capacity and aspects of distress using self-completed questionnaires with the Nottingham Health Profile (NHP) instrument before the operation and 6and 12 months afterwards.
The QOL of the patients who had undergone CABS and PTCA was significantly better on the dimensions of energy, pain, and mobility 1 year after the intervention. In the medication group, the only improvement took place on the dimension of social isolation, whereas both energy and mobility deteriorated.
The results on QOL obtained in this study support the notion that patients continue to have many problems even after medical treatment with a good outcome. The problems occur in different areas compared with the pretreatment situation as on the dimensions of social isolation and emotional reaction. The rehabilitation of CAD patients is therefore important because the new problems are manifested differently from those seen before the illness or the treatment. The patient's QOL and personal preference for a treatment modality should be important criteria in the choice of treatment.
在芬兰,冠状动脉疾病(CAD)给社会带来了相当大的经济负担;在500万人口中,每年约有7500名男性和6500名女性死于该病。
本研究旨在评估药物治疗、经皮腔内冠状动脉成形术(PTCA)和冠状动脉旁路移植术(CABS)治疗的CAD患者在1年期间生活质量(QOL)的变化。
研究人群包括280例CAD患者。100例患者被转诊接受CABS,另外100例接受PTCA,而80例患者接受药物治疗。患者在手术前以及术后6个月和12个月使用诺丁汉健康量表(NHP)通过自行填写问卷,从功能能力和痛苦方面评估他们的健康状况和QOL。
接受CABS和PTCA的患者在干预后1年,在精力、疼痛和活动能力方面的QOL显著改善。在药物治疗组,仅在社会隔离维度有所改善,而精力和活动能力均恶化。
本研究中获得的QOL结果支持这样一种观点,即即使治疗效果良好,患者在治疗后仍存在许多问题。与治疗前相比,这些问题出现在不同领域,如社会隔离和情绪反应维度。因此,CAD患者的康复很重要,因为新出现的问题与疾病或治疗前出现的问题表现不同。患者的QOL和对治疗方式的个人偏好应成为治疗选择的重要标准。