一名慢性淋巴细胞白血病患者的猝死
Sudden death in a patient with chronic lymphocytic leukemia.
作者信息
Beaubien E R, Wilson T W, Satkunam N
机构信息
Department of Medicine, University of Saskatchewan, Saskatoon.
出版信息
CMAJ. 1998 Nov 3;159(9):1123-5.
Abstract
The authors describe a 51-year-old man with chronic lymphocytic leukemia who presented with respiratory distress and then died suddenly while in hospital. Autopsy revealed pulmonary leukostasis and a large intracardiac mass containing mostly mature lymphocytes and fibrin. Although leukostasis and lymphocyte thrombi have been described (albeit rarely) in chronic lymphocytic leukemia, an intracardiac "clot" has not. It seems plausible that this intracardiac mass caused the patient's death.
摘要
作者描述了一名51岁的慢性淋巴细胞白血病男性患者，该患者出现呼吸窘迫，随后在医院突然死亡。尸检发现肺部白细胞淤滞以及一个大的心脏内肿物，其主要由成熟淋巴细胞和纤维蛋白组成。虽然在慢性淋巴细胞白血病中已描述过白细胞淤滞和淋巴细胞血栓形成（尽管很少见），但心脏内“血栓”尚未见报道。这个心脏内肿物导致患者死亡似乎是合理的。
相似文献
1
Sudden death in a patient with chronic lymphocytic leukemia.一名慢性淋巴细胞白血病患者的猝死
CMAJ. 1998 Nov 3;159(9):1123-5.
2
Multicentric glial brain tumors of a varying degree of differentiation in patient with chronic lymphocytic leukemia.
Am J Hematol. 2005 May;79(1):50-3. doi: 10.1002/ajh.20306.
3
[Therapeutic leukapheresis in a leukostasis syndrome complicating chronic lymphoid leukemia].[治疗慢性淋巴细胞白血病并发白细胞淤滞综合征的白细胞去除术]
Ann Med Interne (Paris). 1988;139 Suppl 1:53-4.
4
[Leukostasis syndrome in a case of chronic lymphocytic leukemia].[一例慢性淋巴细胞白血病患者的白细胞淤滞综合征]
Pol Merkur Lekarski. 1999 Jan;6(31):30-1.
5
Hemophagocytic lymphohistiocytosis associated with influenza A (H1N1) infection in a patient with chronic lymphocytic leukemia: an autopsy case report and review of the literature.慢性淋巴细胞白血病患者甲型H1N1流感感染相关噬血细胞性淋巴组织细胞增生症：一例尸检病例报告及文献复习
Ann Diagn Pathol. 2012 Dec;16(6):477-84. doi: 10.1016/j.anndiagpath.2011.03.009. Epub 2011 Jul 2.
6
Renal failure due to T-cell mediated lymphocytic vasculitis: an unusual complication of B-cell chronic lymphocytic leukemia.T细胞介导的淋巴细胞性血管炎所致肾衰竭：B细胞慢性淋巴细胞白血病的一种罕见并发症。
Am J Kidney Dis. 2000 Sep;36(3):E17. doi: 10.1053/ajkd.2000.16219.
7
Sézary syndrome coexisting with B-cell chronic lymphocytic leukemia: case report and review of the literature.蕈样肉芽肿综合征合并B细胞慢性淋巴细胞白血病：病例报告及文献复习
Dermatology. 2008;216(1):68-75. doi: 10.1159/000109362.
8
Acute cardiorespiratory failure as presenting symptom of chronic lymphocytic leukemia.
Neth J Med. 1996 Jul;49(1):33-7. doi: 10.1016/0300-2977(96)00008-3.
9
Sudden death due to leukostasis in a subject with undiagnosed chronic lymphocytic leukemia.患者患有未确诊的慢性淋巴细胞白血病，因白细胞淤滞而突然死亡。
Forensic Sci Med Pathol. 2021 Dec;17(4):693-699. doi: 10.1007/s12024-021-00406-9. Epub 2021 Aug 20.
10
[Treatment of the leukostasis syndrome in chronic lymphadenosis using leukapheresis].[采用白细胞去除术治疗慢性淋巴细胞增多症中的白细胞淤滞综合征]
Vnitr Lek. 1993 Aug;39(8):788-92.
引用本文的文献
1
Sudden death due to leukostasis in a subject with undiagnosed chronic lymphocytic leukemia.患者患有未确诊的慢性淋巴细胞白血病，因白细胞淤滞而突然死亡。
Forensic Sci Med Pathol. 2021 Dec;17(4):693-699. doi: 10.1007/s12024-021-00406-9. Epub 2021 Aug 20.
2
Leukostasis in Chronic Lymphocytic Leukemia.慢性淋巴细胞白血病中的白细胞淤滞。
Am J Case Rep. 2020 Jul 3;21:e924798. doi: 10.12659/AJCR.924798.
本文引用的文献
1
Thrombosis and hemorrhage in oncology patients.
Hematol Oncol Clin North Am. 1996 Aug;10(4):875-907. doi: 10.1016/s0889-8588(05)70374-9.
2
Acute cardiorespiratory failure as presenting symptom of chronic lymphocytic leukemia.
Neth J Med. 1996 Jul;49(1):33-7. doi: 10.1016/0300-2977(96)00008-3.
3
Chronic lymphocytic leukemia.慢性淋巴细胞白血病
Cancer Treat Rev. 1996 Jan;22(1):1-13. doi: 10.1016/s0305-7372(96)90013-4.
4
Complement-induced granulocyte aggregation: an unsuspected mechanism of disease.补体诱导的粒细胞聚集：一种未被察觉的疾病机制。
N Engl J Med. 1980 Apr 3;302(14):789-94. doi: 10.1056/NEJM198004033021407.
5
Therapeutic cytapheresis in chronic lymphocytic leukemia.慢性淋巴细胞白血病的治疗性血细胞分离术。
J Clin Apher. 1983;1(4):243-8. doi: 10.1002/jca.2920010408.
6
Intravascular leukocyte thrombi and aggregates as a cause of morbidity and mortality in leukemia.血管内白细胞血栓和聚集体是白血病发病和死亡的一个原因。
Medicine (Baltimore). 1974 Nov;53(6):463-78. doi: 10.1097/00005792-197411000-00006.
7
Rheology of leukocytes, leukocyte suspensions, and blood in leukemia. Possible relationship to clinical manifestations.白血病中白细胞、白细胞悬液及血液的流变学。与临床表现的可能关系。
J Clin Invest. 1973 Feb;52(2):350-8. doi: 10.1172/JCI107191.
8
Pulmonary leukostasis: radiologic-pathologic study.肺白细胞淤滞症：放射学-病理学研究
Radiology. 1987 Dec;165(3):739-41. doi: 10.1148/radiology.165.3.3479813.
9
Leucostasis, an underestimated cause of death in leukaemia.
Blut. 1988 Jan;56(1):39-44. doi: 10.1007/BF00321058.
10
[Therapeutic leukapheresis in a leukostasis syndrome complicating chronic lymphoid leukemia].[治疗慢性淋巴细胞白血病并发白细胞淤滞综合征的白细胞去除术]
Ann Med Interne (Paris). 1988;139 Suppl 1:53-4.
Zotero 插件