Feldman M J, Linzey E M, Srebnik E, Kent D R, Goldstein A I, Nelson M
Am J Obstet Gynecol. 1976 Oct 15;126(4):418-21. doi: 10.1016/0002-9378(76)90629-3.
Abnormal cervical cytology is being discovered in an alarming number of sexually active teen-agers. Over an 18 month period, cytology consistent with mild dysplasia or worse was noted in 188 of 2,655 teen-agers screened. This represents a rate of 70.8 per thousand. Colposcopically directed biopsies in 65 patients revealed 15 cases of severe dysplasia-carcinoma in situ. Cryosurgery was the principle method of treatment and, combined with colposcopy, is a safe and effective means of managing these patients.