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社区中接受美沙酮维持治疗的麻醉药品成瘾者的临床抑郁症。

Clinical depression among narcotic addicts maintained on methadone in the community.

作者信息

Weissman M M, Slobetz F, Prusoff B, Mezritz M, Howard P

出版信息

Am J Psychiatry. 1976 Dec;133(12):1434-8. doi: 10.1176/ajp.133.12.1434.

Abstract

In a study of 106 predominantly young, lower-social-class men participating in a methadone maintenance program, the authors found that about one-third were moderately to severely depressed as assessed on standard rating scales of depression. The depressive symptoms were associated with a decrease in social functioning, increase in stress in the past 6 months, and a history of alcohol abuse. Because the combination of depression and drug addiction creates a high risk for suicide, depressive symptoms require early detection and treatment. The authors point to the need for more research on treatment approaches, particularly the use of psychotropic drugs.

摘要

在一项针对106名主要为年轻的、社会阶层较低且参与美沙酮维持治疗项目的男性的研究中,作者发现,根据标准抑郁评定量表评估,约三分之一的人有中度至重度抑郁。抑郁症状与社会功能下降、过去6个月压力增加以及酗酒史有关。由于抑郁和药物成瘾共同作用会产生很高的自杀风险,因此抑郁症状需要早期发现和治疗。作者指出需要对治疗方法进行更多研究,尤其是使用精神药物。

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