Weissman M M, Slobetz F, Prusoff B, Mezritz M, Howard P
Am J Psychiatry. 1976 Dec;133(12):1434-8. doi: 10.1176/ajp.133.12.1434.
In a study of 106 predominantly young, lower-social-class men participating in a methadone maintenance program, the authors found that about one-third were moderately to severely depressed as assessed on standard rating scales of depression. The depressive symptoms were associated with a decrease in social functioning, increase in stress in the past 6 months, and a history of alcohol abuse. Because the combination of depression and drug addiction creates a high risk for suicide, depressive symptoms require early detection and treatment. The authors point to the need for more research on treatment approaches, particularly the use of psychotropic drugs.
在一项针对106名主要为年轻的、社会阶层较低且参与美沙酮维持治疗项目的男性的研究中,作者发现,根据标准抑郁评定量表评估,约三分之一的人有中度至重度抑郁。抑郁症状与社会功能下降、过去6个月压力增加以及酗酒史有关。由于抑郁和药物成瘾共同作用会产生很高的自杀风险,因此抑郁症状需要早期发现和治疗。作者指出需要对治疗方法进行更多研究,尤其是使用精神药物。