Rainer G, Asaad W F, Miller E K
Department of Brain and Cognitive Sciences and The Center for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15008-13. doi: 10.1073/pnas.95.25.15008.
Many prefrontal (PF) neurons convey information about both an object's identity (what) and its location (where). To explore how they represent conjunctions of what and where, we explored the receptive fields of their mnemonic activity (i.e., their "memory fields") by requiring monkeys to remember both an object and its location at many positions throughout a wide portion of central vision. Many PF neurons conveyed object information and had highly localized memory fields that emphasized the contralateral, but not necessarily foveal, visual field. These results indicate that PF neurons can simultaneously convey precise location and object information and thus may play a role in constructing a unified representation of a visual scene.
许多前额叶（PF）神经元能传递有关物体身份（是什么）及其位置（在哪里）的信息。为了探究它们如何表征“是什么”和“在哪里”的结合信息，我们通过要求猴子在中央视觉的很大一部分区域内的多个位置记住一个物体及其位置，来探索其记忆活动的感受野（即它们的“记忆场”）。许多PF神经元传递物体信息，并且具有高度局部化的记忆场，这些记忆场强调对侧视野，但不一定是中央凹视野。这些结果表明，PF神经元可以同时传递精确的位置和物体信息，因此可能在构建视觉场景的统一表征中发挥作用。
