Styrud J, Eriksson S, Granström L
Department of Surgery, Karolinska Institutet at Danderyd Hospital, Danderyd, Sweden.
Dig Surg. 1998;15(6):683-6. doi: 10.1159/000018678.
In a retrospective study 2,351 records from patients who underwent surgery for acute appendicitis during 1986-1993 were analysed. During this period, there were 362 patients with perforated appendicitis. The aim of this study was to analyse the complication rate, the period of antibiotic treatment and whether the complication rate decreased when intravenous treatment was followed by oral antibiotic treatment.
The complication frequency was 18% which was significantly higher than that for non-perforated appendicitis of 10%. The complication rate was 15% in the group receiving additional oral antibiotics compared to 19% in the group receiving only intravenous antibiotics. This difference is not significant.
Perforated appendicitis is however still associated with increased mortality and morbidity.
在一项回顾性研究中，对1986年至1993年间接受急性阑尾炎手术的2351例患者的记录进行了分析。在此期间，有362例患者患有穿孔性阑尾炎。本研究的目的是分析并发症发生率、抗生素治疗时间，以及静脉治疗后改用口服抗生素治疗时并发症发生率是否降低。
并发症发生率为18%，显著高于非穿孔性阑尾炎的10%。接受额外口服抗生素治疗的组并发症发生率为15%，而仅接受静脉抗生素治疗的组为19%。这种差异不显著。
然而，穿孔性阑尾炎仍然与死亡率和发病率的增加有关。
