面向生物学家的10万个蛋白质结构。
100,000 protein structures for the biologist.
作者信息
Sali A
机构信息
Laboratories of Molecular Biophysics, The Rockefeller University, New York, New York 10021, USA.
出版信息
Nat Struct Biol. 1998 Dec;5(12):1029-32. doi: 10.1038/4136.
DOI:10.1038/4136
PMID:9846869
Abstract
Structural genomics promises to deliver experimentally determined three-dimensional structures for many thousands of protein domains. These domains will be carefully selected, so that the methods of fold assignment and comparative protein structure modeling will result in useful models for most other protein sequences. The impact on biology will be dramatic.
摘要
结构基因组学有望为成千上万的蛋白质结构域提供通过实验确定的三维结构。这些结构域将经过精心挑选，以便折叠分类和比较蛋白质结构建模的方法能够为大多数其他蛋白质序列生成有用的模型。对生物学的影响将是巨大的。
Zotero 插件