Srinivasarao G Y, Yeh L S, Marzec C R, Orcutt B C, Barker W C, Pfeiffer F
Protein Information Resource, National Biomedical Research Foundation, 3900 Reservoir Road N.W., Washington, DC 20007, USA.
Nucleic Acids Res. 1999 Jan 1;27(1):284-5. doi: 10.1093/nar/27.1.284.
The Protein Information Resource (PIR) has been maintaining a database of curated protein sequence alignments since 1991. The collection includes superfamily, family and homology domain alignments. CLUSTAL V/W is used to generate multiple sequence alignments and ALNED, an interactive alignment editor, is used to check and correct them. The database has helped in classifying sequences, in defining new homology domains, and in spreading and standardizing protein names, features and keywords among members of a family or superfamily. The ATLAS information retrieval system can be used to browse and query the PIR-ALN alignments. The quarterly and weekly updates can be accessed via the WWW at http://www-nbrf. georgetown.edu/pir/
蛋白质信息资源库（PIR）自1991年以来一直在维护一个经过整理的蛋白质序列比对数据库。该集合包括超家族、家族和同源结构域比对。CLUSTAL V/W用于生成多序列比对，而交互式比对编辑器ALNED用于检查和纠正这些比对。该数据库有助于序列分类、定义新的同源结构域，以及在一个家族或超家族的成员之间传播和规范蛋白质名称、特征和关键词。ATLAS信息检索系统可用于浏览和查询PIR-ALN比对。季度和每周更新可通过万维网在http://www-nbrf.georgetown.edu/pir/上获取。
