Périer R C, Junier T, Bonnard C, Bucher P
Swiss Institute of Bioinformatics & Swiss Institute for Experimental Cancer Research, Ch. des Boveresses 155, 1066-Epalinges s/Lausanne, Switzerland.
Nucleic Acids Res. 1999 Jan 1;27(1):307-9. doi: 10.1093/nar/27.1.307.
The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukaryotic POL II promoters, for which the transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in nucleotide sequence entries. The annotation part of an entry includes description of the initiation site mapping data, cross-references to other databases, and bibliographic references. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis. Recent efforts have focused on exhaustive cross-referencing to the EMBL nucleotide sequence database, and on the improvement of the WWW-based user interfaces and data retrieval mechanisms. EPD can be accessed at http://www.epd.isb-sib.ch
真核生物启动子数据库（EPD）是一个经过注释的非冗余真核生物聚合酶II启动子集合，其转录起始位点已通过实验确定。通过指向核苷酸序列条目中的位置的指针来提供对启动子序列的访问。条目的注释部分包括起始位点定位数据的描述、与其他数据库的交叉引用以及文献参考。EPD的结构便于动态提取具有生物学意义的启动子子集以进行比较序列分析。最近的工作重点是与EMBL核苷酸序列数据库进行详尽的交叉引用，以及改进基于万维网的用户界面和数据检索机制。可通过http://www.epd.isb-sib.ch访问EPD。
