Suyama M, Nagase T, Ohara O
Kazusa DNA Research Institute, 1532-3 Yana, Kisarazu, Chiba 292-0812, Japan.
Nucleic Acids Res. 1999 Jan 1;27(1):338-9. doi: 10.1093/nar/27.1.338.
HUGE is a database for human large proteins newly identified by Kazusa cDNA project, which aims to predict protein primary structures from sequences of human large cDNAs (>4 kb). In particular, cDNA clones capable of coding for large proteins (>50 kDa) are current targets of the project. More than 700 sequences of human cDNAs (average size, 5.1 kb) have been determined to date and deposited in the public databases. Notable information implied from the cDNAs and the predicted protein sequences can be obtained through HUGE via the World Wide Web at URL http://www.kazusa.or.jp/huge
HUGE是一个关于由Kazusa cDNA项目新鉴定出的人类大蛋白的数据库,该项目旨在从人类大cDNA(>4 kb)序列预测蛋白质一级结构。特别是,能够编码大蛋白(>50 kDa)的cDNA克隆是该项目目前的目标。迄今为止,已测定了700多条人类cDNA序列(平均大小为5.1 kb)并存入公共数据库。通过万维网,可在网址http://www.kazusa.or.jp/huge通过HUGE获取从cDNA和预测的蛋白质序列中得到的显著信息。