Schorr S J, Chawla A, Devidas M, Sullivan C A, Naef R W, Morrison J C
Department of Maternal-Fetal Medicine, Women's and Children's Hospital, Lafayette, LA 70508, USA.
J Perinatol. 1998 Nov-Dec;18(6 Pt 1):427-30.
To evaluate the differences in sleep of women throughout pregnancy compared with those of nonpregnant control subjects.
Four pregnant women were studied longitudinally during their pregnancy using inpatient polysomnography. Measurements included electroencephalography, electrocardiography, and continuous-pulse oximetry. Four healthy nonpregnant women matched for age and weight were used as control subjects. The total sleep time was recorded, and percentages of each sleep stage were generated.
Qualitative differences in sleep between pregnancy patients and control subjects were evident. Control subjects displayed a normal appearance of slow-wave sleep in stages 3 and 4 (delta sleep). When pregnant patients did display delta sleep, it appeared abnormal secondary to extensive alpha-wave intrusion. Even when including this abnormal delta sleep in a quantitative comparison, the pregnant patients had a significantly shorter percentage of total sleep time in delta sleep (4.9+/-1.9% vs 21.9+/-6.0%, p=0.03).
Sleep in pregnancy is characterized by loss of normal slow-wave sleep. Thus, sleep stages 3 and 4 are shortened during pregnancy. This sleep alteration is persistent when followed longitudinally during pregnancy.
评估孕期女性与非孕期对照者在睡眠方面的差异。
对4名孕妇在孕期进行纵向研究，采用住院多导睡眠监测。测量指标包括脑电图、心电图和连续脉搏血氧饱和度测定。选取4名年龄和体重匹配的健康非孕期女性作为对照者。记录总睡眠时间，并计算每个睡眠阶段的百分比。
孕期患者与对照者在睡眠方面存在明显的质性差异。对照者在3期和4期（慢波睡眠）呈现出正常的慢波睡眠表现。孕期患者即使出现慢波睡眠，也因广泛的α波侵入而显得异常。即使将这种异常的慢波睡眠纳入定量比较，孕期患者慢波睡眠占总睡眠时间的百分比也显著更低（4.9±1.9% 对 21.9±6.0%，p = 0.03）。
孕期睡眠的特征是正常慢波睡眠缺失。因此，孕期3期和4期睡眠阶段缩短。这种睡眠改变在孕期纵向随访过程中持续存在。
