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Proton pump inhibitors may mask early gastric cancer. Dyspeptic patients over 45 should undergo endoscopy before these drugs are started.

作者信息

Griffin S M, Raimes S A

出版信息

BMJ. 1998 Dec 12;317(7173):1606-7. doi: 10.1136/bmj.317.7173.1606.

DOI:10.1136/bmj.317.7173.1606
PMID:9848895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1114430/
Abstract
摘要

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Proton pump inhibitors may mask early gastric cancer. Dyspeptic patients over 45 should undergo endoscopy before these drugs are started.质子泵抑制剂可能会掩盖早期胃癌。45岁以上的消化不良患者在开始使用这些药物之前应接受内镜检查。
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本文引用的文献

1
The response of early gastric cancer to proton-pump inhibitors.早期胃癌对质子泵抑制剂的反应。
N Engl J Med. 1998 Jun 25;338(26):1924-5. doi: 10.1056/NEJM199806253382616.
2
Improving the detection rate of early gastric cancer requires more than open access gastroscopy: a five year study.提高早期胃癌的检出率需要的不仅仅是开放式胃镜检查：一项为期五年的研究。
Gut. 1997 Sep;41(3):308-13. doi: 10.1136/gut.41.3.308.
3
Delays in the diagnosis of oesophagogastric cancer: a consecutive case series.食管癌和胃癌的诊断延误：连续病例系列研究
BMJ. 1997 Feb 15;314(7079):467-70. doi: 10.1136/bmj.314.7079.467.
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Gastric cancer: a curable disease in Britain.胃癌：在英国可治愈的疾病。
BMJ. 1993 Sep 4;307(6904):591-6. doi: 10.1136/bmj.307.6904.591.
5
Guidelines on appropriate indications for upper gastrointestinal endoscopy. Working Party of the Joint Committee of the Royal College of Physicians of London, Royal College of Surgeons of England, Royal College of Anaesthetists, Association of Surgeons, the British Society of Gastroenterology, and the Thoracic Society of Great Britain.上消化道内镜检查的适宜指征指南。由伦敦皇家内科医师学院、英格兰皇家外科医师学院、皇家麻醉师学院、外科医师协会、英国胃肠病学会和大不列颠胸科学会联合委员会工作小组制定
BMJ. 1995 Apr 1;310(6983):853-6. doi: 10.1136/bmj.310.6983.853.
6
Natural history of "early" gastric cancer: results of a 10-year regional survey.“早期”胃癌的自然史：一项为期10年的区域调查结果
Br Med J. 1980 Oct 11;281(6246):965-7. doi: 10.1136/bmj.281.6246.965.
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Prospective study of "early" gastric cancer.“早期”胃癌的前瞻性研究。
Int J Cancer. 1983 Apr 15;31(4):421-6. doi: 10.1002/ijc.2910310405.
8
Early detection of gastric cancer.胃癌的早期检测
BMJ. 1990 Sep 15;301(6751):513-5. doi: 10.1136/bmj.301.6751.513.
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Misleading response of malignant gastric ulcers to cimetidine.恶性胃溃疡对西咪替丁的误导性反应。
Lancet. 1978 Apr 1;1(8066):686-8. doi: 10.1016/s0140-6736(78)90799-7.