Davies E L, Gateley C A, Miers M, Mansel R E
Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, UK.
J R Soc Med. 1998 Sep;91(9):462-4. doi: 10.1177/014107689809100903.
Mastalgia is a common condition in women of reproductive years. We have assessed the long-term course in patients with severe mastalgia by distributing a postal questionnaire to 212 patients previously studied in 1983 who had attended the mastalgia clinic at the University Hospital of Wales, Cardiff. 175 patients (83%) responded, with an original diagnosis of cyclical mastalgia (CM) in 120 and non-cyclical mastalgia (NCM) in 55. The median age of onset of breast pain was 36 years (range 12-63 years). The average duration of pain was long (median 12 years), especially if it started in the second or third decade of life. Pain persisted in 68 (57%) of CM and 35 (64%) of NCM patients. In CM patients resolution was commonly associated with a 'hormonal' event, notably the menopause; in NCM patients it more often seemed to be spontaneous. Severe mastalgia ran a chronic relapsing course often requiring repeated drug treatments.
乳房疼痛是育龄期女性的常见病症。我们通过向212名曾于1983年在威尔士大学医院加的夫乳房疼痛诊所就诊的患者发放邮寄问卷,评估了严重乳房疼痛患者的长期病程。175名患者(83%)回复了问卷,其中120名最初诊断为周期性乳房疼痛(CM),55名诊断为非周期性乳房疼痛(NCM)。乳房疼痛的中位发病年龄为36岁(范围12 - 63岁)。疼痛的平均持续时间较长(中位值为12年),尤其是如果疼痛始于生命的第二个或第三个十年。68名(57%)CM患者和35名(64%)NCM患者的疼痛持续存在。在CM患者中,疼痛缓解通常与“激素”事件有关,尤其是绝经;在NCM患者中,疼痛缓解似乎更常是自发的。严重乳房疼痛呈慢性复发病程,常需反复药物治疗。