Oldenhave A, Jaszmann L J, Everaerd W T, Haspels A A
Faculty of the Social Sciences, Department of Women Studies, Leiden University, The Netherlands.
Am J Obstet Gynecol. 1993 Mar;168(3 Pt 1):765-71. doi: 10.1016/s0002-9378(12)90816-9.
Our purpose was to compare the severity of typical climacteric complaints (vasomotor complaints and vaginal dryness) and 21 other complaints, considered atypical for the climacteric, in women with and without a uterus.
A cross-sectional population questionnaire survey was sent to all women aged 39 through 60 years in Ede, the Netherlands. Subjects were 986 hysterectomized women (one or both ovaries present) and 5636 normal women (uterus and both ovaries present). Statistical analysis was performed by cross tabulations, chi 2 analysis, analysis of variance, meta-analysis of variance, and ratios.
Hysterectomized women, especially those aged 39 to 41 years, report significantly more vasomotor complaints, vaginal dryness, and atypical complaints than do normal climacteric women of the same age. The higher prevalence of typical climacteric complaints in hysterectomized women largely explains their higher level of atypical complaints.
Physicians should be alert to typical climacteric complaints after hysterectomy with ovarian conservation, especially in young women, because the literature indicates that hysterectomized women with ovarian conservation are overrepresented with regard to osteoporosis, cardiovascular disease, osteoarthritis, depression, and sexual problems.
我们的目的是比较有子宫和无子宫女性中典型更年期症状（血管舒缩症状和阴道干燥）以及另外21种被认为是非典型更年期症状的严重程度。
向荷兰埃德市所有39至60岁的女性发送了一份横断面人群问卷调查。研究对象为986名接受子宫切除术的女性（保留一个或两个卵巢）和5636名正常女性（子宫和两个卵巢均保留）。通过交叉表、卡方分析、方差分析、方差的元分析和比率进行统计分析。
接受子宫切除术的女性，尤其是39至41岁的女性，与同龄正常更年期女性相比，报告的血管舒缩症状、阴道干燥和非典型症状明显更多。接受子宫切除术的女性中典型更年期症状的较高患病率在很大程度上解释了她们较高水平的非典型症状。
医生应对保留卵巢的子宫切除术后的典型更年期症状保持警惕，尤其是在年轻女性中，因为文献表明，保留卵巢的子宫切除术后女性在骨质疏松症、心血管疾病、骨关节炎、抑郁症和性问题方面的比例过高。
