Blaxter M
Institute of Cell, Animal, and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK.
Science. 1998 Dec 11;282(5396):2041-6. doi: 10.1126/science.282.5396.2041.
Caenorhabditis elegans is a rhabditid nematode. What relevance does this have for the interpretation of the complete genome sequence, and how will it affect the exploitation of the sequence for scientific and social ends? Nematodes are only distantly related to humans and other animal groups; will this limit the universality of the C. elegans story? Many nematodes are parasites; can knowledge of the C. elegans sequence aid in the prevention and treatment of disease?
秀丽隐杆线虫是一种小杆线虫。这对于完整基因组序列的解读有何关联,又将如何影响该序列为科学和社会目的的利用?线虫与人类及其他动物群体的亲缘关系较远;这会限制秀丽隐杆线虫研究成果的普遍性吗?许多线虫是寄生虫;秀丽隐杆线虫序列的知识能有助于疾病的预防和治疗吗?