Kanauchi O, Mitsuyama K, Saiki T, Fushikia T, Iwanaga T
Applied Bioresearch Center, Corporate Research and Development Division, Kirin Brewery Co. Ltd., Takasaki, Gunma 370-12, Japan.
Int J Mol Med. 1998 Jun;1(6):937-41. doi: 10.3892/ijmm.1.6.937.
Germinated barley foodstuff (GBF), derived from the aleurone layer, scutellum and germ of germinated barley, contains a large quantity of fermentable dietary fibers, especially hemicellulose. Ten grams of GBF were given to 10 healthy volunteers 3 times a day (30 g/day/person) for 28 consecutive days. Fecal weight, water contents and short chain fatty acid content were measured before GBF administration and from days 25 to 28 after initiation of GBF administration. GBF intake significantly increased fecal butyrate content as well as fecal weight and water content. No significant change in body weight resulted from consumption of GBF for 28 days. No major laboratory abnormalities were found in hematologic and urinary analysis. These findings indicate that GBF promotes defecation, produces bacterial short chain fatty acids, especially butyrate, without adverse effects, and is a safe foodstuff for humans.
发芽大麦食品（GBF）源自发芽大麦的糊粉层、盾片和胚芽，含有大量可发酵膳食纤维，尤其是半纤维素。连续28天，每天3次给10名健康志愿者每人10克GBF（每人每天30克）。在服用GBF前以及开始服用GBF后第25天至28天测量粪便重量、水分含量和短链脂肪酸含量。摄入GBF显著增加了粪便丁酸盐含量以及粪便重量和水分含量。食用GBF 28天体重无显著变化。血液学和尿液分析未发现重大实验室异常。这些发现表明，GBF可促进排便，产生细菌短链脂肪酸，尤其是丁酸盐，且无不良影响，是一种对人体安全的食品。
