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发芽大麦食品可改善洛哌丁胺诱导的大鼠便秘。

Germinated barley foodstuff improves constipation induced by loperamide in rats.

作者信息

Kanauchi O, Hitomi Y, Agata K, Nakamura T, Fushiki T

机构信息

Applied Bioresearch Center, Corporate Research and Development Division Kirin Brewery Co. Ltd., Gunma, Japan.

出版信息

Biosci Biotechnol Biochem. 1998 Sep;62(9):1788-90. doi: 10.1271/bbb.62.1788.

DOI:10.1271/bbb.62.1788
PMID:9805382
Abstract

The effects of germinated barley foodstuff (GBF) derived from the aleurone and scutellum fractions of germinated barley low-lignified hemicellulose were examined in Sprague-Dawley rats with constipation induced by loperamide by addition to the diet (2 mg/kg body weight). Bowel movements were higher in the GBF-fed rats than in the cellulose-fed rats used as a control. Fecal water content was also higher in the GBF-fed rats. The concentration of short chain fatty acids in cecal content, especially butyrate, was significantly higher in the GBF-fed rats than in the cellulose-fed rats. These findings suggested that GBF helps normalize defecation not only in diarrhea but also constipation.

摘要

研究了发芽大麦低木质化半纤维素糊粉层和盾片部分衍生的发芽大麦食品(GBF)对洛哌丁胺诱导便秘的Sprague-Dawley大鼠的影响,方法是在饮食中添加GBF(2毫克/千克体重)。喂食GBF的大鼠的排便次数高于用作对照的喂食纤维素的大鼠。喂食GBF的大鼠的粪便含水量也更高。喂食GBF的大鼠盲肠内容物中短链脂肪酸的浓度,尤其是丁酸盐,显著高于喂食纤维素的大鼠。这些发现表明,GBF不仅有助于腹泻时排便正常化,也有助于便秘时排便正常化。

相似文献

1
Germinated barley foodstuff improves constipation induced by loperamide in rats.发芽大麦食品可改善洛哌丁胺诱导的大鼠便秘。
Biosci Biotechnol Biochem. 1998 Sep;62(9):1788-90. doi: 10.1271/bbb.62.1788.
2
Preventive effect of germinated barley foodstuff on diarrhea induced by water-soluble dietary fiber in rats.
Biosci Biotechnol Biochem. 1997 Mar;61(3):449-54. doi: 10.1271/bbb.61.449.
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Germinated barley foodstuff increases fecal volume and butyrate production at relatively low doses and relieves constipation in humans.发芽大麦食品在相对低剂量时可增加粪便体积和丁酸盐产量,并缓解人类便秘。
Int J Mol Med. 1998 Oct;2(4):445-50. doi: 10.3892/ijmm.2.4.445.
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Effects of germinated barley foodstuff on dextran sulfate sodium-induced colitis in rats.发芽大麦食品对葡聚糖硫酸钠诱导的大鼠结肠炎的影响。
J Gastroenterol. 1998 Apr;33(2):179-88. doi: 10.1007/s005350050067.
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Effects of germinated barley foodstuff in preventing diarrhea and forming normal feces in ceco-colectomized rats.
Biosci Biotechnol Biochem. 1998 Feb;62(2):366-8. doi: 10.1271/bbb.62.366.
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Germinated barley foodstuff increases fecal volume and butyrate production in humans.发芽大麦食品可增加人体粪便体积并提高丁酸盐产量。
Int J Mol Med. 1998 Jun;1(6):937-41. doi: 10.3892/ijmm.1.6.937.
7
The dietary combination of germinated barley foodstuff plus Clostridium butyricum suppresses the dextran sulfate sodium-induced experimental colitis in rats.发芽大麦食品与丁酸梭菌的饮食组合可抑制葡聚糖硫酸钠诱导的大鼠实验性结肠炎。
Scand J Gastroenterol. 2000 Oct;35(10):1060-7. doi: 10.1080/003655200451180.
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Effect of germinated barley foodstuff administration on mineral utilization in rodents.发芽大麦食品对啮齿动物矿物质利用的影响。
J Gastroenterol. 2000;35(3):188-94. doi: 10.1007/s005350050329.
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Increased growth of Bifidobacterium and Eubacterium by germinated barley foodstuff, accompanied by enhanced butyrate production in healthy volunteers.发芽大麦食品可增加双歧杆菌和真杆菌的生长,并使健康志愿者体内的丁酸产量增加。
Int J Mol Med. 1999 Feb;3(2):175-9. doi: 10.3892/ijmm.3.2.175.
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Lactic acid fermentation of germinated barley fiber and proliferative function of colonic epithelial cells in loperamide-induced rats.发芽大麦纤维的乳酸发酵和洛哌丁胺诱导大鼠结肠上皮细胞的增殖功能。
J Med Food. 2010 Aug;13(4):950-60. doi: 10.1089/jmf.2009.1307.

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