Romanova L K, Pokrovskaia M S, Mladkovskaia T B, Kulikova G V, Volkova E V, Safronova L A, Zhorova E S, Beliaev I K, Gerasiuto G I, Sivakoba I S
Research Institute of Human Morphology, Moscow.
Arkh Patol. 1998 Sep-Oct;60(5):32-6.
The possibility of transplacental passage of Cr-90 and Cs-137 as well as their traces appearance in descendants muscles and bones beginning from the 2nd pregnancy trimester (and this was sometimes associated with teratogenic effects) was demonstrated on the abortion material (human embryos and fetuses) from the controlled zones of the Bryansk region. Statistically significant inhibition of the bronchial branching (according to the morphometry of the lung histological section) this indicating the disturbance of the lung prenatal morphogenesis during the "pseudoglandular" developmental stage was observed in the 1st trimester of the pregnancy in the descendants of the irradiated mothers. Lung hypoplasia was observed in some cases in the 2nd and 3rd trimesters of the pregnancy. Activation of lymphoid cells in the fetal lungs and the tendency to the enhancement in them of the ectopic erythroid hemopoiesis was revealed. These processes are considered as a reflection of the compensatory adaptive cellular reaction in the descendants respiratory organs in response to the tissue hypoxia and antigenic stimuli from the organism of the pregnant woman irradiated after the Chernobyl accident.
在布良斯克地区控制区的人工流产材料（人类胚胎和胎儿）上证实了铬-90和铯-137经胎盘传递的可能性，以及从妊娠中期开始它们在后代肌肉和骨骼中出现痕迹（这有时与致畸效应有关）。在受照母亲的后代妊娠早期，观察到支气管分支有统计学意义的抑制（根据肺组织切片形态计量学），这表明在“假腺期”发育阶段肺产前形态发生受到干扰。在妊娠中期和晚期的某些病例中观察到肺发育不全。发现胎儿肺中淋巴细胞活化以及异位红细胞生成有增强的趋势。这些过程被认为是切尔诺贝利事故后受照孕妇机体组织缺氧和抗原刺激导致后代呼吸器官代偿性适应性细胞反应的一种体现。
