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利用超快磁共振成像进行胎儿畸形的产前诊断。

Prenatal diagnosis of fetal malformations by ultrafast magnetic resonance imaging.

作者信息

Kubik-Huch R A, Wisser J, Stallmach T, Ladd M E, Meier A, Marincek B

机构信息

Department of Radiology, University Hospital Zürich, Switzerland.

出版信息

Prenat Diagn. 1998 Nov;18(11):1205-8. doi: 10.1002/(sici)1097-0223(199811)18:11<1205::aid-pd429>3.0.co;2-b.

DOI:10.1002/(sici)1097-0223(199811)18:11<1205::aid-pd429>3.0.co;2-b
PMID:9854735
Abstract

Prenatal ultrasonography is the primary imaging modality in pregnancy as it allows direct real-time fetal examination. Antenatal magnetic resonance imaging (MRI) has so far been of limited clinical value owing to poor image quality. This was due to the long acquisition times that were needed to achieve a high enough spatial resolution for assessment of the small fetal anatomic structures resulting in severe motion artefacts. This problem has now been overcome by recent technical improvements. We present a case of fetal malformation (MURCS association), where an ultrafast T2-weighted RARE sequence (single shot fast spin echo sequence) provided images of excellent quality, which led to the correct antenatal diagnosis. MRI using this sequence can now be used for prenatal diagnosis and is thus likely to become an important adjunct to ultrasonography, especially in cases in which ultrasound findings are unclear of sonographic images are impaired by maternal obesity or oligohydramnios.

摘要

产前超声检查是孕期主要的成像方式,因为它能对胎儿进行直接实时检查。迄今为止,产前磁共振成像(MRI)由于图像质量差,临床价值有限。这是因为需要较长的采集时间才能获得足够高的空间分辨率来评估胎儿的小解剖结构,从而导致严重的运动伪影。最近的技术改进现已克服了这个问题。我们报告一例胎儿畸形(MURCS综合征)病例,其中超快T2加权RARE序列(单次激发快速自旋回波序列)提供了高质量图像,从而实现了正确的产前诊断。使用该序列的MRI现在可用于产前诊断,因此很可能成为超声检查的重要辅助手段,尤其是在超声检查结果不明确或超声图像受孕妇肥胖或羊水过少影响的情况下。

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