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昼行性和夜行性物种角膜上皮中的抗坏血酸盐。

Ascorbate in the corneal epithelium of diurnal and nocturnal species.

作者信息

Ringvold A, Anderssen E, Kjønniksen I

机构信息

Eye Department, National Hospital, University of Oslo, Norway.

出版信息

Invest Ophthalmol Vis Sci. 1998 Dec;39(13):2774-7.

PMID:9856789
Abstract

PURPOSE

To compare the amount of ascorbic acid in the corneal epithelium of various species to unveil possible differences between diurnal and nocturnal mammals.

METHODS

Ascorbic acid was determined by high-performance liquid chromatography, using an LC-10 system (Shimadzu, Kyoto, Japan).

RESULTS

Diurnal animals show a higher ascorbate concentration in the corneal epithelium than nocturnal animals. Ascorbate concentration is higher in the corneal epithelium than in the matching aqueous humor in diurnal and nocturnal species. The highest ascorbate concentration is found in the corneal epithelium of the reindeer.

CONCLUSIONS

Ascorbate level in the corneal epithelium seems to vary in accordance with ambient radiation exposure of the respective species, just as in the aqueous humor. Both phenomena are regarded as environmental adaptations, and the ascorbic acid is suggested as protecting against photokeratitis and as acting as an ultraviolet filter for internal eye structures.

摘要

目的

比较不同物种角膜上皮中抗坏血酸的含量,以揭示昼行性和夜行性哺乳动物之间可能存在的差异。

方法

使用LC - 10系统(日本京都岛津公司)通过高效液相色谱法测定抗坏血酸。

结果

昼行性动物角膜上皮中的抗坏血酸盐浓度高于夜行性动物。在昼行性和夜行性物种中,角膜上皮中的抗坏血酸盐浓度高于相应的房水。驯鹿角膜上皮中的抗坏血酸盐浓度最高。

结论

角膜上皮中的抗坏血酸盐水平似乎与各物种的环境辐射暴露情况有关,房水也是如此。这两种现象都被视为环境适应性变化,抗坏血酸被认为可预防光性角膜炎,并作为眼内结构的紫外线滤过剂。

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