van den Berg H
TNO Nutrition and Food Research Institute, Zeist, Netherlands.
Int J Vitam Nutr Res. 1998;68(6):360-5.
Carotenoid interactions during absorption and in postabsorptive metabolism have been observed in both human and animal studies. We reviewed the mutual interactions reported between lutein and beta-carotene and report new data on the postprandial beta-carotene and retinyl ester response in the triglyceride-rich plasma lipoprotein (TRL) fraction in volunteers after a single test meal with beta-carotene alone, or beta-carotene combined with lutein or lycopene. Results indicate an inhibitory effect of lutein on beta-carotene absorption, but apparently not on beta-carotene cleavage. In a comparative study with two beta-carotene/lutein ratios (2:1 and 1:2, respectively), this inhibitory effect of lutein was found to be most marked when lutein was the predominant carotenoid. In studies on plasma (serum) response also an inhibitory effect of beta-carotene on lutein response was observed.
在人体和动物研究中均观察到了类胡萝卜素在吸收过程中和吸收后代谢过程中的相互作用。我们回顾了叶黄素和β-胡萝卜素之间相互作用的相关报道，并报告了志愿者在单独食用β-胡萝卜素，或β-胡萝卜素与叶黄素或番茄红素组合的单一测试餐后，富含甘油三酯的血浆脂蛋白（TRL）部分中餐后β-胡萝卜素和视黄酯反应的新数据。结果表明，叶黄素对β-胡萝卜素的吸收有抑制作用，但显然对β-胡萝卜素的裂解没有抑制作用。在一项关于两种β-胡萝卜素/叶黄素比例（分别为2:1和1:2）的对比研究中，发现当叶黄素是主要类胡萝卜素时，叶黄素的这种抑制作用最为明显。在血浆（血清）反应研究中，也观察到了β-胡萝卜素对叶黄素反应的抑制作用。
