Chilton W S, Ott J
Lloydia. 1976 Mar-Jun;39(2-3):150-7.
Forty-seven specimens representing 35 species or varieties of Amanita were examined for the presence of ibotenic acid, muscimol, stizolobic acid, stizolobinic acid, aminohexadienoic acid and chlorocrotylglycine. In addition, crude extracts of A. muscaria were examined chromatographically for the presence of methyltetrahydrocarboline carboxylic acid (MTC). Ibotenic acid and muscimol were found in clearly detectable concentrations in extracts of A. cothurnata, all specimens of A. muscaria, all specimens of A. pantherina and in lower concentrations in A. gemmata. Stizolobic acid and stizobinic acid were found in detectable concentrations in one variety of A. muscaria, in all specimens of A. pantherina and in trace levels after additional purification of the extracts in A. gemmata and in the remaining specimens of A. muscaria. Aminohexadienoic acid and chlorocrotylglycine were detected only in crude extracts of A. smithiana. MTC could not be detected in crude extracts of A. muscaria. Crystalline ibotenic acid (820 mg) was isolated from 17 kg of a specimen of A. pantherina collected in western Washington State.
对代表35种或变种鹅膏菌的47个标本进行了检查，以确定是否存在鹅膏蕈氨酸、蝇蕈醇、刀豆氨酸、刀豆氨酸、氨基己二烯酸和氯巴豆酰甘氨酸。此外，对毒蝇伞的粗提物进行了色谱分析，以确定是否存在甲基四氢咔啉羧酸（MTC）。在橙盖鹅膏菌的提取物、所有毒蝇伞标本、所有豹斑鹅膏菌标本中均发现了浓度明显可检测到的鹅膏蕈氨酸和蝇蕈醇，在宝石红鹅膏菌中浓度较低。在一种毒蝇伞变种、所有豹斑鹅膏菌标本中发现了浓度可检测到的刀豆氨酸和刀豆氨酸，在宝石红鹅膏菌和其余毒蝇伞标本的提取物经过进一步纯化后发现了痕量水平的刀豆氨酸和刀豆氨酸。仅在史密斯鹅膏菌的粗提物中检测到氨基己二烯酸和氯巴豆酰甘氨酸。在毒蝇伞的粗提物中未检测到MTC。从华盛顿州西部采集的17千克豹斑鹅膏菌标本中分离出了820毫克结晶鹅膏蕈氨酸。
