Eichmiller F C, Marjenhoff W A
American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA.
Oper Dent. 1998 Sep-Oct;23(5):218-28.
In the 1940s, dentists observed that secondary caries was rarely associated with silicate cement restorations. While the relatively stable dimensional properties of those restorations were undoubtedly a factor in this fortunate circumstance, the fact that fluoride was inherent in the composition of the material received the greater credit. By the mid-1980s, a wide variety of fluoride-releasing dental restorative materials were available to dentists and dental consumers, and the cariostatic effect of fluoride ions on enamel caries had been demonstrated in many studies. This paper reviews much of the fluoride-related research conducted on fluoride-releasing amalgam, glass-ionomer cements, composites, primers, sealants, liners, acrylic resins, and orthodontic bracket bonding materials. The need for standardization of test methods is addressed, as is the need for more controlled clinical trials and additional research.
20世纪40年代，牙医观察到继发龋很少与硅酸盐粘固粉修复体相关。虽然这些修复体相对稳定的尺寸特性无疑是造成这种幸运情况的一个因素，但材料成分中固有的氟化物这一事实得到了更多认可。到20世纪80年代中期，牙医和牙科消费者可以使用各种各样的释氟牙科修复材料，并且许多研究已经证明了氟离子对牙釉质龋的防龋作用。本文回顾了对释氟汞合金、玻璃离子粘固粉、复合材料、底漆、窝沟封闭剂、衬层、丙烯酸树脂和正畸托槽粘结材料进行的许多与氟相关的研究。文中讨论了测试方法标准化的必要性，以及进行更严格的临床试验和更多研究的必要性。
