Stanhope N, Guinan E, Kopelman M D
Psychology Department, Institute of Psychiatry, London, UK.
Neuropsychologia. 1998 Dec;36(12):1387-96. doi: 10.1016/s0028-3932(98)00040-2.
Patients with diencephalic, temporal lobe or frontal lobe lesions were compared with healthy controls on a frequency judgement task. The three patient groups were disproportionately impaired at estimating how often a series of abstract designs had been presented relative to controls. Diencephalic and temporal lobe patients did not differ from each other. It is argued that the results may reflect a 'core' memory deficit in the temporal lobe patients. The impairment in the frontal patients may reflect their difficulty in making an organised search in memory for multiple traces of an item, while the deficit shown by the diencephalic patients (particularly those with Korsakoff syndrome) may be due to the combined effects of a generally poor memory and superimposed frontal pathology.
在一项频率判断任务中，对患有间脑、颞叶或额叶病变的患者与健康对照组进行了比较。与对照组相比，这三组患者在估计一系列抽象图案的呈现频率方面受损程度不成比例。间脑和颞叶患者之间没有差异。有人认为，这些结果可能反映了颞叶患者存在“核心”记忆缺陷。额叶患者的损伤可能反映出他们难以在记忆中进行有组织的搜索以找到某个项目的多个痕迹，而间脑患者（特别是患有科萨科夫综合征的患者）所表现出的缺陷可能是由于总体记忆较差和叠加的额叶病变共同作用的结果。
