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耐辐射细菌耐辐射奇异球菌Sark的肽聚糖精细结构

Peptidoglycan fine structure of the radiotolerant bacterium Deinococcus radiodurans Sark.

作者信息

Quintela J C, García-del Portillo F, Pittenauer E, Allmaier G, de Pedro M A

机构信息

Centro de Biología Molecular "Severo Ochoa," Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Facultad de Ciencias, Campus de Cantoblanco, 28049 Madrid, Spain.

出版信息

J Bacteriol. 1999 Jan;181(1):334-7. doi: 10.1128/JB.181.1.334-337.1999.

Abstract

Peptidoglycan from Deinococcus radiodurans was analyzed by high-performance liquid chromatography and mass spectrometry. The monomeric subunit was: N-acetylglucosamine-N-acetylmuramic acid-L-Ala-D-Glu-(gamma)-L-Orn-[(delta)Gly-Gly]-D-Ala-D-Ala. Cross-linkage was mediated by (Gly)2 bridges, and glycan strands were terminated in (1-->6)anhydro-muramic acid residues. Structural relations with the phylogenetically close Thermus thermophilus are discussed.

摘要

通过高效液相色谱和质谱分析法对耐辐射球菌的肽聚糖进行了分析。其单体亚基为:N-乙酰葡糖胺-N-乙酰胞壁酸-L-丙氨酸-D-谷氨酸-γ-L-鸟氨酸-[(δ)甘氨酰-甘氨酸]-D-丙氨酸-D-丙氨酸。交联由(Gly)2桥介导,聚糖链以(1→6)脱水胞壁酸残基结尾。文中讨论了与亲缘关系较近的嗜热栖热菌的结构关系。

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